A6140

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A6140

Sigma

 

Ampicillin trihydrate

96.0-100.5%

Synonym:D-(−)-α-Aminobenzylpenicillin
CAS Number:7177-48-2
Linear Formula:C16H19N3O4S · 3H2O
Molecular Weight:403.45
Beilstein Registry Number:5399534
EC Number:200-709-7
MDL number:MFCD00072036
PubChem Substance ID:24891059

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Description

Biochem/physiol ActionsA β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

Properties

assay96.0-100.5%
mp198-200 °C (dec.)(lit.)
storage temp.2-8°C

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard CodesXn
Risk Statements36/37/38-42/43
Safety Statements22-26-36/37
WGK Germany2
RTECSXH8425000

References

MerckMerck 13,591
referenceCorp MSDS 1 (1), 247:B / RegBook 1 (2), 2065:I / Sigma FT-IR 1 (1), 619:C / Structure Index 1, 328:B:3